I'm running Lyceum 0.34 on Apache 2.0.59 with PHP 4.3.10 and MySQL 4.1, all on Windows Server 2003.
Well, after finally getting PHP working, MySQL working, and then realizing I should never have even tried using IIS 6, I installed Apache 2 and mod_rewrite (and, of course, Lyceum). I've followed all the directions at http://wiki.lyceum.ibiblio.org/index.php/Troubleshooting and created a .htaccess in my /src/lyceum (and changed the RewriteBase to match).
Unfortunately, I already had the following in my httpd.conf: <code> DocumentRoot "C:\Inetpub\wwwroot\lyceum-blogs" ... <Directory "/src/lyceum"> Options Indexes FollowSymLinks Multiviews AllowOverride All Order allow,deny Allow from all </Directory> </code>